This guide discusses current advances in theoretical-computational research on the biosynthesis of melanin pigment (melanogenesis). These advances are being pushed by the event of high-performance computer systems, new experimental findings, and intensive work on medical functions involving the management of pigmentation and the therapy of difficult dermatological illnesses. Understanding the elementary processes concerned in chemical reactions on the atomic scale is essential in biochemical response design for efficient management of the pigmentary system. Accordingly, the guide focuses on the elementary steps concerned in melanogenesis, which crucially have an effect on the composition of the ensuing melanin pigment by way of aggressive reactions. The guide additionally addresses reactions analogous to melanogenesis, with a concentrate on o-quinone reactions, that are particularly essential for understanding melanogenesis-associated cytotoxicity.
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